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Dosing, if needed
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Usual dose: 2 mg/d IV
Maximum dose: 10 mg/d
Contraindications: Hepatotoxicity, hypertension, history of thrombophilia, and pregnancy
Maximum daily dose: 80 mg
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6-18 Years:
Infants:
Dose: 2 mg intravenous
Subsequent doses: 2 mg intravenous
Age 6 to 12 Years:
Dose: 2 mg orally daily between meals for a total of 4 to 6 mg/kg/day.
12 years:
Age 12 and older:
Mehram (1 to 2 times a week): 4.0 to 14.2 mg orally per day for children 2 years and older.
Maximum daily dose: 17.4 mg orally per day divided in two dose forms: oral tablet (25 mg) and intravenous injection (5 to 10 mg/kg body weight every 12 h for children 6 months to 2 years).
Maximum dose: 26.8 mg orally per day divided in two dose forms: oral tablet (25 mg) and intravenous injection (5 to 10 mg/kg body weight every 12 h for children 6 months to 2 years).
Maximum dose: 26.8 mg orally per day subdivided into 2 dose forms: oral tablet (25 mg) and intravenous injection (5 to 10 mg/kg body weight every 6 h).
Maximum daily dose: 29.4 mg oral tablet (25 mg) daily divided into 2 dose forms: oral tablet (25 mg) and intravenous injection (5 to 10 mg/kg/day).
Maximum daily dose: 35.0 mg oral tablet (25 mg) daily divided into 2 dose forms: oral tablet (25 mg) and intravenous injection (5 to 10 mg/kg/day).
6 to 18 Years:
Dose: 20 to 40 mg orally once a day
2 to 5 Years:
4 to 6 mg orally once a day
2-5 Years:
Dose: 5 to 10 mg orally once a day
6 to 12 Years:
5-6 years:
Dose: 10 mg orally twice daily (maximum 50 mg)
3 to 6 Years:
Dose: 25 mg orally once daily
2-4 Years:
4-6 Years:
3-6 Months:
Dose: 20 mg orally thrice daily
3-5 Years:
3-6 Years:
5 Years:
3-12 Years:
2-6 months:
2-6 Months:
2-7 weeks:
2-7 Weeks:
2-10 Weeks:
6 to 12 Months:
3-12 Months:
1-3 Months:
1-4 Months:
1-2 Years:
6 Months:
0 to 2 Years:
Usual Adult Dose for Pediatric Patients:
0.2 to 1 mg/kg orally once daily if needed (maximum 3 times a day).
0.1 to 0.2 mg IV twice a day if needed
Pediatric Patients:
Age 1 to 7 Years:
Infant: 100 mg/kg/dose twice a day orally
1 to 2 Years:
Infant: 50 to 75 mg/kg/dose orally per day from 3 to 10, then 50 70 mg/kg/dose orally from day 11 to 22.
For Children 2 to 5 Years:
Infant: 100 to 150 mg/kg/dose orally (maximum 75 if fed only solids). an additional dose of 100 mg is necessary a separate oral dose should be administered every 6 h. Children 5 to 18 Years: Oral dose: 75 mg IV twice a day, maximum 400 mg in 24 hours at 2-
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